Chemical interference by drugs and other substances with clinical laboratory test procedures.
نویسندگان
چکیده
منابع مشابه
Interference in laboratory tests
Interference in clinical laboratory testing can create discrepancies in test results which can lead to patient harm. In clinical chemistry, interference is defined as a cause of medically significant difference in the measurand test result due to another component or property of the sample. Interference by endogenous and exogenous substances with assays for clinical analytes is a common prob...
متن کاملInterference with clinical laboratory analyses.
Interference by endogenous and exogenous substances with assays for clinical analytes is a common problem in laboratory medicine. For this review, we defined interference as "the effect of a substance present in the sample that alters the correct value of the result, usually expressed as concentration or activity, for an analyte." There are four major endogenous compounds that consistently inte...
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References 1. Khayam-Bashi, H., and Sims, C., Effect of sodium aside on the quantitation of chemical constituents of serum. Am. ,J. Clin. Pat hol. 69, 405 (1978). 2. Khayam-Bashi, H., Sims, C., and Parekh, A. C., Interference of sodium azide with the quantitation of serum cholesterol: A comparative study. Clin. Chim. Acta 66, 69 (1976). 3. Queen, A., and Frings, C. S., Effect of sodium azide on...
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Dear Editor, erythrocyte sedimentation rate (ESR) is a useful basic clinical pathology laboratory investigation. It can be helpful in diagnosis and follow-up of several diseases. At present, a new automated method with proven reliability is available for ESR test (1). Here, the authors report on observation on a laboratory experiment to test the effect of zinc nanoparticles on ESR results. The...
متن کاملInterferences in immunoassay.
Substances that alter the measurable concentration of the analyte or alter antibody binding can potentially result in immunoassay interference. Interfering, endogenous substances that are natural, polyreactive antibodies or autoantibodies (heterophiles), or human anti-animal antibodies together with other unsuspected binding proteins that are unique to the individual, can interfere with the rea...
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عنوان ژورنال:
- Clinica chimica acta; international journal of clinical chemistry
دوره 41 شماره
صفحات -
تاریخ انتشار 1972